Finale: The Last Minutes of Smads

Finale: The Last Minutes of Smads

TGF-beta ligands induce phosphorylation of receptor-activated Smads at both the C-terminal tail and the linker region. Two papers from Massagué and colleagues (Alarcón et al., 2009; Gao et al., 2009) reveal a dual role for this linker phosphorylation, which is required for activation of Smads and for their degradation.

The Last Eight Minutes of a Primordial Black Hole

About eight minutes before a black hole expires it has a decreasing mass of 10 g, an increasing temperature of 1 TeV, and an increasing luminosity of 7× 10 erg/s. I show that such a black hole is surrounded by a quasi-stationary shell of matter undergoing radial hydrodynamic expansion. The inner radius of this shell is bounded by ten times the Schwarzschild radius of 1.6× 10 fm and has a temper...

Finale: Attaining Excellence

Diplomarbeit Finale Endversion_2011-05-03

Can We Remember Future Actions yet Forget the Last Two Minutes? Study in Transient Global Amnesia

Transient global amnesia (TGA) is a clinical syndrome characterized by the abrupt onset of a massive episodic memory deficit that spares other cognitive functions. If the anterograde dimension is known to be impaired in TGA, researchers have yet to investigate prospective memory (PM)--which involves remembering to perform an intended action at some point in the future--in this syndrome. Further...